Scientists print first 3D heart using a patient’s own cells

A tiny heart is made in a 3D printer in a process developed by Tel Aviv University scientists

Israeli Scientists 3D-Print A Tiny Live Heart Made With Human Tissue By No Camels Team

They then mixed the cells and the hydrogel to create so-called "bio-inks" for cardiac patches, which were followed by an entire heart.

A NY woman previously diagnosed with a rare bone cancer has received a 3D-printed sternum and rib cage produced by the CSIRO and Anatomics.

The heart, which is similar to a rabbit heart in size, has demonstrated the potential of the 3D printing technology for producing personalized tissues and organs.

The team isn't ready to print a human-sized heart at this time; the heart they have printed is the size of a rabbit's heart.

Prof Dvir stressed the importance of the heart being made with the patient's own cells and biological materials in order to eliminate the risk of implant rejection.

"This is the first time anyone anywhere has successfully engineered and printed an entire heart replete with cells, blood vessels, ventricles and chambers", lead researcher Tal Dvir, a material scientist and professor of molecular cell biology at TAU, said in a news release.

"This heart is made from human cells and patient-specific biological materials", said Dvir, a researcher at the Sagol Center for Regenerative Biotechnology at Tel Aviv University in Israel. He worked with Prof. The study was published in the journal Advanced Science. For patients with late stage heart failure, a heart transplant is the only solution. In Israel and the United States, many patients die while on the waiting list, hoping for a chance at survival.

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A 3D image displays a computerised visualization of a human heart. The cellular material from the tissues was used as the bionic ink for the printer.

The scientists allege that the small heart is the world's first engineered vascular heart ever made with a 3D printer, according to CBS News.

A biopsy of fatty tissue was taken from patients to ultimately create a patient-specific 3D heart, according to the study.

Cells from a patient's omentum tissue are separated and processed into a personalized thermoresponsive hydrogel. These tissue samples were experimentally reprogrammed to become "pluripotent" or de-identified stem cells.

The tiny organ, now only the size of a cherry, was engineered from the tissue of patients which was use to create a bio-ink.

Researchers must now teach the printed hearts "to behave" like real ones. "In fact, this method allows us to print any organ that is required for a transplant and we believe that this method opens the door to future technologies, which will make the need for organ donors completely unnecessary". With this achievement, the researchers at Tel Aviv University theorised that organ printers could be available at hospitals as early as within 10 years.

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