Nathan Redmond was at the double, either side of Willy Boly's reply for Nuno's side, and Shane Long wrapped things up for the Saints.
The win, along with losses for Cardiff and Brighton, means they are eight points clear of the relegation zone with five matches left to play.
"He knows that I demand a lot from him, not only with the ball but also without".
"I'm absolutely pleased with the win".
"I think they are a very good opponent".
"I gave them a wake-up call at half-time even though we were leading 2-1, because we were not courageous enough and we had a long way to go".
We deserved this win because we were the better team.
Iain Glen cast as Bruce Wayne on Titans
Titans producers explained Glen's version of Bruce Wayne as a much older man, but just as driven to fight for what is right. Esai Morales has recently been confirmed to join the cast in season 2 as Slade Wilson.
They return to league action at Southampton today and Nuno (right) said: "You have to organise your thoughts, and what we feel now is pride".
"The pressure lifts when you win, and then you can celebrate with the fans".
"We are back at Molineux in the next game and we have to bounce back".
Redmond added: "Wolves have had a fantastic season and maybe this was a hangover from last week's (FA) Cup defeat but we had to concentrate on ourselves".
"Marbella was something we planned one month ago, to push the positives of going away before the final run of the season".
"Those were the moments we played better".
Hasenhuttl brought on Long for Ings in the second half, and the substitute notched his second goal in as many games by flicking home from Maya Yoshida's pass.