Former Liverpool captain Tommy Smith has died at the age of 74, the club announced on Friday.
"It is very sad to see him go but his memories will be there forever".
The former footballer was however first diagnosed with Alzheimer's disease in 2014, the same illness his wife suffered from before she passed away four years ago as reported by SunSport.
"He had been growing increasingly frail and suffering from a variety of ailments over the last three months especially".
Perhaps his most famous goal came in the 1977 European Cup final, when Liverpool beat Borussia Monchengladbach 3-1 to lift the trophy for the first time.
"He was an incredible figure who helped me out enormously".
Though Tommy's hard reputation went before him - "born a man, he was never a boy" quipped Shankly - his game included no shortage of finesse and he fell just short of a half-century of Liverpool goals, including season-highs of seven on two occasions.
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Football pundit Michael Owen has led the tributes to the Liverpool star on Twitter.
In a story on Liverpool's official website the club said: "The thoughts of everyone at Liverpool Football Club are with Tommy's family and many friends".
Former Liverpool player and manager Kenny Dalglish added: "He was a great advert for Liverpool Football Club, the way he conducted himself".
Smith, nicknamed the "Anfield Iron" spent 18 years with Liverpool, and took part in both their first FA Cup and European Cup triumphs.
Arguably his biggest goal came toward the end of his run with Liverpool, as he scored the victor in the 1977 European Cup final over Borussia Monchengladbach.
'We are obviously all devastated'.
Since Smith's time patrolling the defence, Liverpool have featured plenty of talented centre-halves as part of the back line.
"Tommy is survived by [daughter] Janette, son Darren and four grandchildren, Matthew, William, Jessica and Imogen", Liverpool said in a statement.