A major spring storm has brought warnings and advisories from Utah to MI, the National Weather Service said. "We will set some records", said Mike Connelly, a weather service meteorologist in Aberdeen, South Dakota.
Just last month, a bomb cyclone hit many of these same areas, including Colorado, Wyoming, North Dakota, South Dakota and Nebraska.
Some areas of western Minnesota and southeast South Dakota could see as much as 30 inches (76 cm) of snow.
Parts of Nebraska, South Dakota and Minnesota are under a blizzard warning and parts of Colorado, Kansas and Utah are under a freeze warning.
The World-Herald noted, however, that the storm forecast to hit this week could be "just shy" of the definition of a bomb cyclone.
To the south in parts of Texas, New Mexico and Oklahoma, the storm will cause high winds, with wind gusts potentially reaching up to 75 miles per hour.
According to the National Oceanic and Atmospheric Administration, a bomb cyclone - or bombogenesis - occurs when a cold air mass collides with a warm arm mass, causing the atmospheric pressure of a storm to drop 24 millibars in less than 24 hours. The deluge resulted in more than $3 billion in damage to property and crops in Nebraska and Iowa alone.
In some states, getting from one point to another will be a nightmare.
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High spring temperatures will give way to heavy snow, gale-force winds and life-threatening conditions across a swathe of the central United States running from the Rockies to the Great Lakes, according to the National Weather Service. A video from the Minnesota Department of Transportation shows every power line down along a length of Highway 59 near Fulda, in the southeastern side of the state.
Whiteout conditions on roadways were making "travel extremely risky", according to the weather service. Of those, 33 involved injuries, authorities tweeted.
The Minnesota State Patrol said it had responded to more than 500 crashes statewide since Wednesday, while the National Guard stood ready to rescue any stranded motorists. Denver saw a near record high of 78 degrees on Tuesday. By Wednesday, temperatures were in the mid- to upper 30s.
The Minneapolis/St. Paul area may be spared blizzard conditions but still could see up to 5 inches of snow. Many school districts in Colorado and Wyoming canceled or shortened classes.
The snowfall could lead to additional flooding in the region.
The Red River is experiencing significant flooding because of melting snow, with this new storm likely prolonging the high water. Residents were urged to stay home and avoid travel unless necessary.
Frontier said customers whose flights are canceled may request a refund.