Cardi B had one of the show's memorable performances, twerking on a piano and strutting with peacock-like plumage attached to her hips while singing "Money".
Cardi B took the stage at the Staples Center holding the hand of husband, Offset, with whom she has reunited after marital issues a year ago.
Just shortly after his baby mama's big win, Offset took to social media to reveal the release date of his upcoming solo album and its supporting documentary.
"I'm sick of this shit".
She went on to talk about being nominated previous year for "Bodak Yellow", but she didn't win any awards for the song.
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Quickly, Grande clarified that she was not attempting to rain on Cardi's moment, instead was upset that her ex-bae Mac Miller was not awarded, citing his family was invited to the ceremony and the effort he put into the album.
"My album went #1 and spend [sic] 21 weeks straight on billboard top ten!" Number 1 album as well.
She added that not only did she pour her heart and soul into the record but she did it while being pregnant and keeping that a secret from the industry.
"I had like, three songs that I was for sure having - you know how it was". We know you're pregnant.
"I wanna thank my daughter", Cardi said during her speech.
And thus the New Yorker began clocking her rapid ascent to stardom: as her profile grew, Cardi in 2015 gave up stripping to give rap a go.