Joe Flacco threw for 238 yards and a touchdown for Baltimore.
Ahead of Sunday's clash with the Ravens, Mariota admitted it would be tough facing the NFL's third best defence this year. It didn't help as Mariota was sacked the most in his four-year National Football League career. We're going to try to take what we have and give them the best opportunity to go make some plays.
The Titans (3-3) have little time to address the offensive problems before leaving for the franchise's first game in London against the Los Angeles Chargers (4-2).
Long after many of his teammates had already boarded the team bus at Nissan Stadium on Sunday evening, Ravens outside linebacker Terrell Suggs returned to his locker, where a group of reporters waited.
And now they head home for four of their next five games.
Asked whether he has ever been in a game like that, Mariota said, "No, that was a first".
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Offensive guard Alex Lewis was immobilized and taken off the field in the fourth quarter on a stretcher after suffering a neck injury.
Mariota was the first player in over 30 years to complete 10 passes while being sacked over 10 times. The Titans get their bye when they return from London before a visit to Dallas and a home game November 11 against New England.
In rushing, Alex Collins ran for 54 yards and two touchdowns in 19 carries while Gus Edwards added 42 yards in 10 carries.
So protecting him is of utmost importance for the Tennessee Titans. Baltimore had 11 total in a dominating victory in Nashville.
The Baltimore Ravens had a serious scare Sunday night against the Tennessee Titans.
Flacco lined up as a wide receiver and even though the Titans were not going to get fooled into thinking that the quarterback will be a receiver on that play, especially with that kind of pre-snap stance, Tennessee still failed to stop Jackson from uncorking a 22-yard run.