In the interview, the Cambridge Democrat, who has said she will "take a hard look" at running for president after November 6, placed the DNA results within the context of other recent moves she's made to open her background to outside scrutiny.
She said she released the results "because I've got nothing to hide".
Warren released test results of a DNA analysis earlier this week that showed she had a distant Native American ancestry. The percentages that have been reported range from 1/64 to 1/1,032 Native American.
However, when Warren entered politics her story gained deeper scrutiny and began to unravel.
Trump simply doubled down attacks he'd been making for years, simultaneously belittling Warren and Native Americans. In the infrastructure of systemic racism she has not experienced the same discrimination that a person of color has experienced. And that is fine.
Warren in 1984 contributed five recipes to a Native American cookbook called "Pow Wow Chow", according to Politifact.
Powerline blogger John Hinderaker wrote /a: "If Warren is an Indian, then so are most of the rest of us".
Warren's DNA test is the weakest attempt to legitimize claims to Native heritage with.09 percent.
Another claim in Trump's tweet bears correcting. In his own statement, the secretary of state for the Cherokee Nation said Ms. Warren's use of DNA undermines tribal governments, which are in constant battle with the United States for sovereignty. "Sen. Warren is undermining tribal interests with her continued claims of tribal heritage".
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Ultimately, Warren's tests showed she likely has less Native American blood than the average white American.
The release of the DNA test was met with widespread criticism, with some conservative leaders pointing to the results as proof of Warren's exaggerated diversity and liberals and tribal leaders condemning the use of race as a political tactic. The Massachusetts lawmaker actually got it right when she made the critical distinction that an ancestral link is not the equivalent of belonging to a Native American community or culture, nor should it entitle people far removed from an ancestor to seek or claim tribal status.
Mr Trump relishes a good fight, those close to him have said, and will hit back twice as hard when he has been attacked.
In fact, not even Cherokees were happy with Warren.
In July, Trump joked that he would "gently" toss her a DNA testing kit if he ever faced Warren in a presidential debate.
Liberal columnist Dana Milbank criticized Warren in the Washington Post.
Again, it's not Trump she'll have to battle.
The test-run of this spectacle was already made during the previous presidency, when Trump repeatedly insisted that Barack Obama was born, not in Hawaii but Kenya.
This week's reveal was also about Republicans, who continue to mock her.