Despite Liverpool sitting top of the Premier League, Klopp said it is not possible for the five-time European Cup winners to put off their Champions League campaign, which begins on Tuesday when Paris Saint-Germain visit Anfield.
Klopp hit back at the former Red Devils skipper by claiming that he did not understand how to concentrate exclusively on one competition when at a club like Liverpool, who are expected to compete on all fronts.
Pochettino's side claimed a 4-1 win over Liverpool in the corresponding fixture of last season but he is anticipating a much tougher task this time around.
"Last year, for example, we had no chance to focus on one competition because we had to qualify for the Champions League and I don't think that even Gary Neville would have said: 'Quarterfinals of the Champions League, let City win'".
"I think he's sensible enough to know that why he has done so well is not just because of the player he is, it's because of Jurgen Klopp's style of play". Klopp asked the reporter during his press conference. His record in cup finals is simply bad as he has now lost six out of his last seven major finals, including that painful 3-1 defeat to Real Madrid in last season's Champions League final.
The former right-back suggested that if the German wants to win the league, he should forget all about the Champions League. Around this time three years ago, Jurgen Klopp took charge of his first game as Liverpool manager, against, you guessed, Spurs.
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After its initial impact, Byard said the most serious concern will be massive rainfalls that would produce risky inland flooding. The homes of about 10 million were under watches or warnings for the hurricane or tropical storm conditions. "We'll handle it.
"To focus on one competition can only be if you are already out, or almost out, or if it's late in the season".
"The thing is it is absolutely no problem". I don't like the situation, because I don't like to say to Fabinho, who is full of energy and desire to play, to tell him he is not involved.
"The most hard [thing] is when you don't have a lot of players", said Klopp. That is not nice, but it is the job.
"It's an incredible build which is going to take time, it's disappointing (Spurs are not playing there yet) and we should have a date".
Liverpool have got off to a great start, winning every game and playing good football.
"It has to be in good shape when we get in it, and if it takes a little bit longer then it takes a little bit longer".