"I told them yesterday for me it's like we start from zero", Spurs manager Pochettino said.
Ryan Fraser and Callum Wilson were the difference makers for the Cherries, handing them an easy win in their season-opener against the newly promoted outfit.
Tottenham had the majority of possession in the first half but couldn't force a two-goal cushion, with defender Sanchez coming closest from a glancing header wide from an Eriksen corner.
But overall, it was an average performance from the former Newcastle midfielder, who is once again expected to go down the pecking order in the Tottenham squadron this season.
MF Moussa Sissoko, 7 - Assigned to the unglamorous role of breaking up the home team's rhythm, Sissoko stuck to his task.
Former Brazilian superstar footballer Ronaldo in intensive care
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Pochettino handed a debut to academy graduate Luke Amos, bringing him on for the "tired" Dier.
Still, Spurs could not have asked for more here. However, apart from a few early touches he appeared at odds with himself and his game, producing few of the driving runs that had earned him a start.
England duo Kieran Trippier and Danny Rose were absent from the squad, while Eric Dier limped off and Lucas Moura was spotted with an ice pack on his groin after being replaced.
MF Christian Eriksen, 6 - Struggled to impose himself on the game, with his contribution limited to flickering cameos. Whipped in some unsafe crosses from dead-ball situations but was otherwise easily contained. Newcastle were mediocre in the first half, but looked like a unsafe side in the final 45 minutes. The telltale sign that all was not well, though, was in his hold-up play as many of his lay-offs were misplaced.
Everton played the entire second half with 10 men after Phil Jagielka was shown a straight red card. Despite the rumours of a move during the transfer window, he looks committed to the cause. Mousa Dembele, Heung-Min Son and Fernanado Llorente are some of the options Pochettino has on the bench.
Spurs failed to do so, and could in turn be looking at another season of falling short in their pursuit of a first Premier League title.